Harm Reduction Therapeutics

We See You

Through the Eyes of RiVive

We See You

Through the Eyes of RiVive

We See You

Through the Eyes of RiVive

We See You

Through the Eyes of RiVive

We See You

Through the Eyes of RiVive

We See You

Through the Eyes of RiVive

If you are a first-time drug user, we see you. If you are someone who uses drugs regularly, we see you. If you are a concerned parent, the child of a parent who uses, a friend, EMS, supporting a harm reduction program, or just concerned about people in your community,

WE SEE ALL OF YOU.

We understand substance use is multilayered and that it comes with inherent risk. Our goal for RiVive is for you to stay alive.

Harm Reduction Therapeutics

People comforting each other in photo collage

In moments of crisis

compassion RiVives®.

RiVive Naloxone HCL Nasal Spray 3 mg
Buy Now
RiVive (R)
RiVive Naloxone HCI Nasal Spray 3 mg is an FDA-approved over-the-counter (OTC) compassionate dose naloxone product. It’s intended for the emergency treatment of opioid overdose and is manufactured right here in the United States. According to the CDC, naloxone is a safe and effective life-saving medication that can reverse an opioid overdose—including heroin and fentanyl.

RiVive is strong enough to save lives with the lowest dose of OTC intranasal naloxone available in the United States, and it reduces the risk of precipitated withdrawal. RiVive offers Compassionate Overdose ResponseTM intended to rescue and not punish the person. Competitive products are formulated with higher doses of naloxone which can increase the risks of precipitated withdrawal symptoms caused from using more naloxone than may be necessary to reverse an overdose.

Harm Reduction Therapeutics, Inc. (HRT) is able to sell RiVive at a low price thanks to our status as the only 501(c)(3) non-profit pharmaceutical company that manufactures naloxone. Our manufacturing cost is our price, we make zero profit on RiVive.

“This allows us to SAVE AS MANY LIVES AS POSSIBLE THAT WOULD OTHERWISE BE LOST TO OPIOID OVERDOSE.”

-Michael R. Hufford, PhD
 Co-Founder & CEO
Made in U.S.A., Manufactured in North Carolina, Packaged in Indiana

How to Administer

Learn how you can save lives with RiVive in 5 easy steps by watching this video.
Please only use as directed.

RiVive: 5 Key Steps in Case of an Overdose
English
Español
Warning: when using this product, some people may experience symptoms when they wake up such as shaking, sweating, nausea, or feeling irritable.

Our Mission

At Harm Reduction Therapeutics, our mission is rooted in compassion. We believe in a world where every life is valued, and where help is within reach for those facing the threat of overdose. With a deep sense of empathy and commitment, we developed RiVive, an OTC naloxone nasal spray to provide life-saving support when it’s needed most. Guided by the understanding that behind every statistic is a person, we bring accessible, compassionate care. Together we can help each other stay alive with RiVive.

Michael R. Hufford, PhD
Co-Founder & Chief Executive Officer

Learn More

“Overdose reversal medications save lives, and no one should lack access because of affordability or availability.”

– White House Office of National Drug Control Policy Director Dr. Rahul Gupta
Source

“We know what strategies work and what we need to do to end this epidemic.”

– U.S. Surgeon General Vivek Murthy
Source

“No one who needs overdose reversal medications should lack access because of costs or availability.”

– White House Office of National Drug Control Policy Director Dr. Rahul Gupta
Source

“This crisis is killing a New Yorker every three hours and is impacting every individual and family in our city and in our nation. No one is spared, even if you think otherwise. If you use drugs, know someone who is using drugs, or might be around drug use, there are simple steps we can take. First, everyone should carry naloxone, get trained to use it and to recognize the signs of overdose…”

– Former Commissioner of the New York City Department of Health and Mental Hygiene Dr. Ashwin Vasan

Source

“In the midst of this fentanyl overdose epidemic, it is important to focus on measures to prevent youth drug use and ensure that every school has naloxone and has prepared its students and faculty to use it.”

-U.S. Secretary of Education Miguel A. Cardona, Ed.D. and White House and Office of National Drug Control Policy Director Dr. Rahul Gupta
Source
Elderly Couple Embracing
Man consoling woman
Hands reaching toward each other with sky in background

Proven to
Save Lives

  1. Avetian, et al. (2018) DOI: 10.1080/03007995.2017.1334637.
  2. Wheeler, E., et al., Opioid Overdose Prevention Programs Providing Naloxone to Laypersons, 2014.
  3. McClellan, C., et al., Opioid-overdose laws association with opioid use and overdose mortality. Addictive Behaviors, 2018. 86: p. 90-95.
  4. Townsend, T., et al., Cost-effectiveness analysis of alternative naloxone distribution strategies: First responder and lay distribution in the United States. International Journal of Drug Policy, 2019.
  • Naloxone has been shown to be successful in reversing overdoses in 98.8% of cases.1
  • The CDC reports that tens of thousands of lives have been saved since 1996.2
  • A national study showed overdose deaths decreased by 14% in states that enacted naloxone access laws.3
  • Statistical modeling indicates that greater naloxone availability could reduce overdose deaths by 21%.4